The Netherlands international scored twice and registered an assist in a comfortable 4-1 win for Arne Slot's side.
Within 11 minutes of what was widely expected to be a one-sided encounter, Liverpool had the lead, with Dominik Szoboszlai finishing brilliantly after dribbling through two Ipswich challenges and firing home from the edge of the box.
The host's momentum was halted by a lengthy stoppage, however, as Ipswich ace Wes Burns required medical attention after sustaining a knee injury in an innocuous clash with Cody Gakpo. He was given a standing ovation as he was stretchered off.
Mohamed Salah swiftly added a second after the restart, netting his 100th Premier League goal at Anfield with an instinctive back-post finish after Gakpo's teasing delivery.
It was 3-0 before half-time, as a brilliant Ryan Gravenberch pass found Szoboszlai, whose shot was saved, although Gakpo reacted quickly to tap in the rebound.
In the second half, naturally, the game lost some of its ebb and flow, with Liverpool essentially playing attack against defence with the camped out Tractor Boys.
It is little surprise Liverpool added a fourth after the hour mark. Trent Alexander-Arnold delivered a trademark cross and Gakpo rose highest to head home.
With two minutes to go, Jacob Greaves pulled a goal back from a corner with an uncontested header, as he shrugged off Harvey Elliott to power a finish home. It was, however, a case of too little too late.
GOAL rates Liverpool's players from Anfield…
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Alisson Becker (6/10):
Barely tested until he had to make a superb 84th-minute save, denying George Hirst. Let down by his defenders as Greaves pulled a goal back. Consistently accurate in his distribution.
Trent Alexander-Arnold (7/10):
Some teasing deliveries. Linked well with Salah and got up and down consistently, claiming an assist for Gakpo's second. Returning to form and deserved a goal, but hit the post.
Ibrahima Konate (7/10):
Fine pass for Szoboszlai before his superb run and finish. Showed his strength to deal with Liam Delap.
Virgil van Dijk (7/10):
Dominant in defence, both in the air and on the ground.
Andrew Robertson (7/10):
Never had anything to worry about defensively. Got forward regularly.
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Ryan Gravenberch (8/10):
Phenomenal pass in the build-up to Gakpo's finish. Strolled around the midfield with real elegance.
Dominik Szoboszlai (9/10):
Scored a superb goal early on to give Liverpool the lead. Relentless with his energy in the centre of the pitch. He has taken his game up a level this season and he ran the show here.
Alexis Mac Allister (8/10):
So tidy and industrious in midfield. Keeps Liverpool ticking over in understated, but vital, fashion.
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Mohamed Salah (9/10):
Superb finish at the back post to convert Gakpo's cross. Some gorgeous touches and flicks. He's otherworldly.
Cody Gakpo (10/10):
Brilliant ball in for Salah to finish and scored twice himself, one a real striker's effort and the other a brilliant header. A superb performance.
Luis Diaz (7/10):
Always willing to run at his man. Twinkle-toed in his dribbling. The least effective of Liverpool's attackers but was perhaps unfortunate in that regard.
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Wataru Endo (6/10):
Replaced Gravenberch. Was clattered almost immediately but recovered to see out the game in midfield.
Darwin Nunez (6/10):
On for Gakpo. The game was won but he challenged Ipswich's backline whenever he had the chance.
Harvey Elliott (5/10):
On for Szoboszlai. Lost Greaves before he headed in Ipswich's consolation.
Jayden Danns (6/10):
Replaced Mac Allister at 4-0.
Federico Chiesa (N/A):
On for Diaz late on.
Arne Slot (8/10):
Got this spot on. Liverpool's first XI dominated and won the game at a canter, and then he was able to make changes and rest key men. They are steaming towards the title at quite some pace.